Indianapolis Colts vs Arizona Cardinals
Head to head
Preview
How it plays out
Indianapolis Colts vs Arizona Cardinals is an inter-conference matchup: the AFC Colts hosting the NFC Cardinals. This projects as a coin flip, 45-55 with the spread at ARI -0.5.
Tactically, Indianapolis Colts will want to lean on stout interior to attack Arizona Cardinals, whose line play is the obvious pressure point. Going the other way, Arizona Cardinals's rangy safety could punish Indianapolis Colts if pass rush goes unaddressed. Expect both staffs, Shane Steichen and Jonathan Gannon, to script around exactly that battle.
Keep an eye on Michael Pittman Jr. (WR) and Kyler Murray (QB): the two most likely to decide it with a single play. With Colts at home, the model already bakes in roughly a field-goal's worth of home-field edge.
Key players
Colts
Cardinals
Frequently asked
Who is favored in Indianapolis Colts vs Arizona Cardinals?
Our model favors the Arizona Cardinals, with a 55% win probability over the Indianapolis Colts (45%). The projected spread is ARI -0.5.
What is the prediction for Colts vs Cardinals?
Our model favors Arizona Cardinals (55%) over Indianapolis Colts (45%), spread ARI -0.5: effectively a toss-up.
What are the moneyline odds for Indianapolis Colts vs Arizona Cardinals?
Implied from our model's win probabilities, the Indianapolis Colts are +122 and the Arizona Cardinals are -122 on the moneyline.
Who are the key players to watch in Colts vs Cardinals?
Watch Jonathan Taylor (RB) for the Colts and Kyler Murray (QB) for the Cardinals.
Is Colts vs Cardinals a divisional game?
No. It is an inter-conference matchup between the AFC Colts and the NFC Cardinals.