Philadelphia Eagles vs San Francisco 49ers

Head to head

Super Bowl odds4.1%4.1%
Power rating9390
Contender tier

Preview

How it plays out

Philadelphia Eagles vs San Francisco 49ers is a cross-division NFC test that could swing the conference picture. On paper this is about as lopsided as it gets: Philadelphia Eagles at 70% to San Francisco 49ers's 30%, spread PHI -2.5.

Tactically, Philadelphia Eagles will want to lean on elite offensive line to attack San Francisco 49ers, whose injury luck is the obvious pressure point. Going the other way, San Francisco 49ers's scheme genius could punish Philadelphia Eagles if wR depth behind Brown goes unaddressed. Whoever wins that exchange likely wins the game.

Keep an eye on Jalen Hurts (QB) and Brock Purdy (QB): the two most likely to decide it with a single play. With Eagles at home, the model already bakes in roughly a field-goal's worth of home-field edge.

Key players

PHI Eagles

JHJalen Hurts
Jalen Hurts
QB · SB MVP
SBSaquon Barkley
Saquon Barkley
RB · All-Pro
ABA.J. Brown
A.J. Brown
WR · Pro Bowl

SF 49ers

BPBrock Purdy
Brock Purdy
QB · Pro Bowl
CMChristian McCaffrey
Christian McCaffrey
RB · OPOY
NBNick Bosa
Nick Bosa
EDGE · DPOY

Frequently asked

Who is favored in Philadelphia Eagles vs San Francisco 49ers?

Our model favors the Philadelphia Eagles, with a 70% win probability over the San Francisco 49ers (30%). The projected spread is PHI -2.5.

What is the prediction for Eagles vs 49ers?

Our model favors Philadelphia Eagles (70%) over San Francisco 49ers (30%), spread PHI -2.5: a clear mismatch on paper.

What are the moneyline odds for Philadelphia Eagles vs San Francisco 49ers?

Implied from our model's win probabilities, the Philadelphia Eagles are -233 and the San Francisco 49ers are +233 on the moneyline.

Who are the key players to watch in Eagles vs 49ers?

Watch Jalen Hurts (QB) for the Eagles and Brock Purdy (QB) for the 49ers.

Is Eagles vs 49ers a divisional game?

No. It is an NFC inter-divisional game (NFC East vs NFC West), not a division rivalry.